ebdt: Evaluation of Binary Diagnostic Test

An R package for calculating quality measures of binary diagnostic tests with confidence intervals.

Overview

This package calculates the point estimate and confidence intervals of diagnostic test quality measures including:

• Sensitivity & Specificity: Test accuracy for positives and negatives
• Predictive Values: PPV and NPV for clinical prediction
• Likelihood Ratios: PLR and NLR for test utility
• Additional measures: Youden Index, Weighted Kappa, Prevalence

Supports both:

• Cohort/Cross-sectional studies: Full parameter set
• Case-Control/Retrospective studies: Limited to Sensitivity, Specificity, Youden Index, and Likelihood Ratios

Installation

# Install from GitHub
remotes::install_github("migmontal/ebdt")

Quick Start

library(ebdt)

# Example: 2x2 contingency table from a diagnostic test study
# TP=95, FP=10, FN=5, TN=290
ebdt(s1=95, r1=10, s0=5, r0=290, conflev=0.95, digits=3)

Features

• Automatic calculation of confidence intervals using appropriate methods
• Support for both cohort and case-control study designs
• Customizable confidence level and decimal precision
• Formatted console output with 2×2 contingency table
• Interactive Shiny app for user-friendly analysis

Documentation

See the online documentation for:

• Function reference
• Usage examples
• Methodological details and references

Website

This repository hosts the website created for the ebdt library. You can view it at the following link:

https://migmontal.github.io/ebdt-webside/

Shiny app

Run the app and perform your calculations:

https://migmontal.shinyapps.io/ebdt/

Authors

• Miguel Angel Montero-Alonso (ORCID: 0000-0002-1214-9035)
• Juan de Dios Luna del Castillo (ORCID: 0000-0002-1854-4968)

Fundings

Plan Propio de Investigación y Transferencia de la Universidad de Granada. 2024. Programa 21. Programa de estimulación a la investigación.

License

MIT License - see LICENSE file for details. Copyright (c) 2026 Universidad de Granada.